Antipsychotics (also known as neuroleptics or major tranquilizers) are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, or disordered thought), in particular in schizophrenia and bipolar disorder, and are increasingly being used in the management of non-psychotic disorders (ATC code N05A).

The word neuroleptic originates from the Greek word "νεῦρον", neuron ("nerve") and lepsis ("seizure" or "fit").